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1.
Revista De Investigaciones-Universidad Del Quindio ; 34:231-237, 2022.
Article in Spanish | Web of Science | ID: covidwho-20238541

ABSTRACT

Education is a formative process of every subject in a society, it is a right recognized in a tangible way. In the school environment, it infers a comprehensive process for all the actors of the student community. One aspect that has developed over time and that has had greater employability since the COVID-19 pandemic was resilience as a means of management and prompt attention to the process of adaptation and impact in the educational field. This document describes, based on legal criteria, the importance of the resilient process, also approached from the conceptual construction framework of various actors, considering educational resilience as an agent of transformative change in academic performance, as well as the importance of continuous training in and for all the actors of the educational community.

2.
Annals of the Rheumatic Diseases ; 82(Suppl 1):899-901, 2023.
Article in English | ProQuest Central | ID: covidwho-20238372

ABSTRACT

BackgroundBelimumab (BLM) is a monoclonal antibody that inhibits B-lymphocyte stimulating factor (BlyS) approved as a specific treatment for systemic lupus erythematosus (SLE) in 2011. We present the experience with BLM in a Spanish cohort with more than 460 patients.ObjectivesTo describe demographic characteristics, efficacy and safety of BLM in patients with SLE in Spanish population since its approval.MethodsDescriptive, retrospective, multicenter study in patients diagnosed with SLE according to EULAR/ACR 2019, SLICC and/or ACR 1997 diagnostic criteria. Data regarding SLE patients treated with BLM were collected from medical records (2011-2022). Demographic features, efficacy, laboratory variables, SLEDAI, renal involvement, steroid dose, administration routes and safety were assessed. To see whether a trend in BLM prescription had changed or not over time, two periods of time were analyzed: 2011-2016 (period1) and 2017-2022 (period2).ResultsBaseline characteristics of patients are summarized in Table 1.A total of 462 patients (36 hospitals) were included, 50.9% were on intravenous (IV), 34% on subcutaneous (SC) and 15.1% switched from IV to SC route. The median number of pre-BLM csDMARD use was 2.0 (2.0-3.0), being hydroxychloroquine (HCQ) the most frequently used (94.5%). Fifty-two patients were treated with IV cyclophosphamide with a median of 6 bolus received. At the time of BLM start, 443 patients were on prednisone with a median dose of 6.2 mg (5.0-10.0). Significant decreases in prednisone dose, SLEDAI and anti-DNA antibodies were observed from baseline until the last visit, whereas complement C3 and C4 values raised (Figure 1). A total of 118 patients (27.4%) had renal involvement with a median proteinuria of 1.0 g/day (0.5-2.4). Renal biopsy was done in 102 out of 118 patients, being class IV (33%), class III (21%) and class V (16%) the most frequently reported. After BLM, 73.3% of these patients improved (median proteinuria of 0.2 g/day (0.1-0.7).In period1, 100 patients started BLM compared to 362 in period2. The median time from SLE diagnosis to BLM begin was 7.1 (4.0-13.7) and 6.2 (2.1 -14.4) years in period1 and period2, respectively (p=0.454). We found a trend to use more csDMARD before BLM treatment in period1: 2.5 (2-3) vs. 2 (2-3) (p=0.088).A total of 143 (30.5%) patients discontinued treatment mostly due to inefficacy (55.9%) and infections (11.9%). In fact, 116 patients developed infections, mostly mild;2 patients died, 16 had COVID-19 and 4 patients developed tumors requiring discontinuation of the drug.ConclusionIn our cohort of SLE patients in a real-world setting, BLM has been effective, safe and seems to be a good choice to treat renal involvement.References[1]Navarra SV, Guzmán RM, Gallacher AE, et al. Lancet. 2011;377(9767):721-31.[2]Stohl W, Hiepe;rt al. Arthritis Rheum. 2012;64(7):2328-37.[3]Furie R, Rovin BH, Houssiau F, et al. N Engl J Med. 2020;383(12):1117-1128.Acknowledgements:NIL.Disclosure of InterestsNone Declared.

3.
Fisioterapia ; 2023.
Article in Spanish | Scopus | ID: covidwho-2304303

ABSTRACT

Introduction: The WHO recommends early rehabilitation and mobilization interventions in patients hospitalized for COVID-19. The benefits of early physiotherapy, during the hospital stay, have not been proven in clinical trials. Objective: To evaluate the effects of early physiotherapy and health education in hospitalized COVID-19 patients, in relation to the symptoms described in previous studies, analyzing differences between groups regarding their physical conditioning, need for oxygen therapy and hospital stay. Methodology: Randomized clinical trial with two arms, developed in hospitalization and intermediate respiratory care units, with COVID-19 patients. Sixty-four patients included in the experimental group (implementation of an early physiotherapy program after 48–72 h of admission) and 62 patients in the control group (usual treatment of the center). Sociodemographic and clinical variables: mMRC, oxygen therapy, MRC-SS, 30 s-STST, FPM, Tinetti, FRAIL Scale and PCFS. They were evaluated on admission, discharge and two months after discharge. Results: The experimental patients had fewer days of admission and conventional oxygen therapy. At discharge, they present a lower risk of falling (72.9% vs. 95.8%) and less weakness in MRC-SS (2.1% vs. 14.6%). At two months they had less frailty (5.0% vs. 14.5%), greater hand grip strength, less dyspnea, better results in 30s-STST and fewer post-COVID limitations (86.5% vs. 96.4%). Conclusión: The intervention of early physiotherapy in COVID-19 patients and the health education received, prevents muscle weakness during admission, improves physical conditioning at discharge and two months later, and reduces the days of hospital stay. ClinicalTrials.gov (NCT05032885). © 2023 Asociación Española de Fisioterapeutas

4.
TECHNO Review. International Technology, Science and Society Review / Revista Internacional de Tecnología, Ciencia y Sociedad ; 11, 2022.
Article in Spanish | Scopus | ID: covidwho-2206436

ABSTRACT

The article analyzes the use that UCM students make of ICT, after two years of the COVID-19 pandemic. It is found that women, more than men, stop doing things to navigate. The youngest university students are the ones who connect the most, sleep less because they are connected and connect to their social networks during classes. The daily management and maintenance of their social networks is not a burden. For personal relationships, men and women prefer face-to-face and binary people indistinctly. The upward trend in digital disconnection continues. © GKA Ediciones, authors.

5.
BMJ Global Health ; 7:A24, 2022.
Article in English | EMBASE | ID: covidwho-1968269

ABSTRACT

Introduction Healthcare workers usually deal with several risk factors that make them prone to some psychological problems, such as anxiety, depression, burnout, or even PSTD. During the COVID-19 pandemic, this situation worsened, so many studies were conducted to highlight the impact of the pandemic on healthcare professionals' mental health. However, just a few of them focused on vulnerability and protective factors. The present study aimed to explore the role of emotion regulation processes on healthcare workers' mental health. Methods A longitudinal study was conducted with Spanish healthcare workers sample (n=57). Data were collected two times: t1 was assessed during the first wave of COVID-19 in Spain (April-May, 2020), and t2, two months later. Symptoms of depression, PSTD, and emotional exhaustion were assessed as symptomatology, whereas demographics, job conditions, and trait and state emotion regulation variables were collected as predictive factors. Results Regression analyses showed that participants with dysfunctional beliefs about sharing and expressing emotions, higher self-criticism, suppression, negative emotions, lower levels of self-acceptance and reassuring toward themselves, and a lack of the ability to relax in their leisure time in t1 experienced higher levels of depression, PSTD and emotional exhaustion in t2, controlling for baseline levels. Moreover, results also pointed out a significant decrease over time in self-support and reappraisal and a significant increase in lack of empathy and having a distant attitude toward others. Discussion Our results suggest that some emotion regulation processes, such as acceptance, self-reassuring, and being able to relax in leisure time could be relevant in the prevention of psychological problems among healthcare professionals. Practical implications of the results will be discussed as these results may help to design psychological intervention programs and promote healthy job conditions that enhance better mental health not only in a critical context but also in their daily work.

6.
ARRANCADA ; 22(42):36-57, 2022.
Article in Spanish | Web of Science | ID: covidwho-1904630

ABSTRACT

The article aims to expose ways of family education aimed at preparing families of Chess practitioners in the initiation phase. It is derived from an ongoing investigation, the results of which contribute to a line of work of the Study Group of School Sports Initiation, of the Faculty of Physical Culture, of the University of Sancti Spiritus "Jose Marti", focused on the search for knowledge theoretical and practical contributions that help to support, from a more scientific and innovative perspective, the role of the family in sports initiation in the spiritual context. The routes are presented in different modalities: workshops, activities, consultancies, recommendations, among others. The research methodology used is based on the dialectical approach, which allows the combination of theoretical methods (analysis-synthesis, historical-logical, induction-deduction), empirical (observation, interview, document analysis, self-assessment scale, analysis group, methodological triangulation) and mathematical-statistical (percentage calculation and descriptive statistics). The situation caused by COVID-19, prevents the experimentation phase of this proposal in the planned stage, but at the moment it is applied in the Sports Complex "Eumelia Abreu Carvajal" of the municipality of Fomento. Preliminary results reveal a very positive assessment of families on the pathways of family education, taking into account the three dimensions that are taken into consideration to assess the level of preparation: acquired knowledge, increased motivation and improved attitudes towards this practice sport in the initiation stage.

7.
Sustainability ; 14(4):9, 2022.
Article in English | Web of Science | ID: covidwho-1732188

ABSTRACT

Background: This study aims to analyze university student motivation during the period of semi-presence-based education due to the COVID-19 pandemic, based on the type of educational material used: Augmented Reality (AR) videos and traditional videos associated with the Flipped Classroom (FC) methodology. Methods: A sample of 129 university students were asked to take the Instructional Materials Motivation Survey (IMMS). Results indicate that participants in the study were generally more motivated by AR educational material than by FC material;although mean motivation levels with both instruments are extremely high, with scores of 4.57 and 5.64 for FC and AR, respectively. Conclusions: Therefore, a conclusion was met which determines that these results are a starting point to continue the research of the motivational impact of using different types of videos in active methodologies.

8.
Revista Medica del Instituto Mexicano del Seguro Social ; 59(5):412-416, 2021.
Article in Spanish | MEDLINE | ID: covidwho-1589945

ABSTRACT

Background: Mental health problems derived from the COVID-19 pandemic, including depression, anxiety, and stress, need to be identified. Objective: To validate and adapt the COVID-19 Anxiety Scale (CAS) into Spanish. Material and methods: A cross-sectional study was carried out in a total of 303 individuals who answered the Covid-19 Anxiety Scale. Antibody tests for SARS-CoV-2 were identified as a secondary comparison. Results: It was carried out the cross-cultural validation process recommended by the American Academy of Orthopeadic Surgeon (AAOS). It was obtained a Cronbach's alpha of 0.8493 (with an average interitem covariance of 0.2620). Conclusions: It was achieved a valid Spanish version of CAS to be used in routine clinical practice.

9.
H-Ermes-Journal of Communication ; 19:263-291, 2021.
Article in English | Web of Science | ID: covidwho-1581926

ABSTRACT

At the end of the 20th century, the disappearance of the great utopias occurs. Crises are favorable moments to imagine better worlds. Social scientists and humanists - because of their knowledge of reality and its possibilities for change - are privileged to visualize the Covid-19 crisis as an opportunity for change and transfer the orientation of change to all of society. This is a transcendental translation for the consolidation of utopia in the social imaginary. This work explores the rehabilitation of utopia in the exceptional circumstances of the pandemic's start by academics. Doing this identifies, classifies, and analyzes the specific proposals that these thinkers have published in the press to move towards a happy world. We note that the pandemic has not managed to rehabilitate the utopia and that the community's proposals for change are fragmented. We consider that this fragmentation is a symptom of micro-stories, which implies a shift towards micro-routes. However, medium-range utopias proliferate in which messages appear insistently and, in that sense, may be reflected in the social imaginary.

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11.
Research and Practice in Thrombosis and Haemostasis ; 5(SUPPL 2), 2021.
Article in English | EMBASE | ID: covidwho-1509146

ABSTRACT

Background : Since the beginning of the SARS-CoV 2 pandemic, there have been many reports of increased incidence of VTE (venous thromboembolism) and arterial events as a complication, which were the basis for the hypothesis that patients should receive higher doses of thromboprophylaxis (TP) or full anticoagulation. Aims : To determine the incidence of thrombotic events (TE) in patients hospitalized for moderate or severe SARS-CoV2 disease (Covid-19). Methods : Retrospective single center cohort study with adult patients with a positive rt-PCR for SARS-CoV2 , included as from the date of hospital admission due to Covid-19 and followed for 90 days or until death. Results : A total of 1621 patients were included. The mean age was 68.7 years (SD 21.1) and 57% (913) were female, of which 6.5% (59) were pregnant. Overall mortality was 21.6% (348). The overall incidence of symptomatic thrombotics events within 90 days was 1.72% (28/1621, 95%CI 1.19-2.49%), whereas the incidence of pulmonary embolism (PE) was 0.98% (15, 95%CI 0.60-0.16%), deep venous thrombosis (DVT) 0.74% (11, 95%CI 0.42-0.12%), ischemic stroke 0.24% (4, 95%CI 0.09-0.65%) and ischemic arterial events 0.06% (1, 95%CI 0.008-0.43%). No acute coronary syndrome events were recorded. Median hospital stay length percentage under adequate TP was 78%. The median time since positive rt-PCR for the thrombotic event to develop was 22 days (IQR 25th-75th 19-43 days). Median hospital stay length percentage under adequate thromboprophylaxis was 78% (IQR 25th-75th 50-89%). Conclusions : Unlike previous reports, the incidence of thrombotic events was low among our patients with moderate or severe Covid-19.

12.
HemaSphere ; 5(SUPPL 2):642, 2021.
Article in English | EMBASE | ID: covidwho-1393421

ABSTRACT

Background: During the follow-up of oral anticoagulation therapy (OAT) with vitamin K antagonists (VKA), the patient undergo invasive procedures. The decision wether to withdraw or maintain the OAT, as well as the needing or not to implement low molecular weight heparin (LMWH) as bridge therapy, will be determined by the patient's thrombotic risk (TR) and the haemorrhagic risk (HR) of the surgery. Aims: To determine the incidence of thrombohemorrhagic complications in the periprocedural of the patient with OAT, limiting the use of LMWH to patients at high TR looking for decreasing bleeding events related to surgery. Methods: Prospective, unicentric and observational study including 200 patients with OAT who had had surgery between December 2019 and February 2021, with a subsequent follow-up of 4 weeks. The periprocedural management of the OAT was carried out in the anticoagulation consultation according to the hospital protocol approved in the Thrombosis Committee, which classifies patients according to TR (High TR: Prosthetic heart valves, atrial fibrillation (AF) with CHA2DS2- VASc score 7-9, Severe rheumatic mitral valvulopathy, Venous Thromboembolism less tan 3 months ago and Severe thrombophilia, define as Leyden's factor V in homozygosis, 20210 prothrombin mutation, protein C, S or antithrombin III deficiency, múltiples deficiencys or Antiphospholipid Syndrome), and surgeries in three groups according to HR. Thus, the VKA is suspended 3 days before the intervention and resumed 24 hours after. The use of LMWH as bridge therapy (BT) is reserved for patients with high TR or suspected active cancer. It starts the moment OAT is suspended and it is reintroduced along with it 24 hours after surgery for 3 days (if there are no bleeding complications). The dose of LMWH is therapeutic (as patients requiring BT are high TR). Given the coagulopathy inherent to COVID infection, no positive COVID patients were included. Results: The median age of the population is 73 (range 33-93). The main reason for anticoagulation is AF (64.5%). Most patients are low TR and HR on the CHADs-VASc and HAS-BLED scales (76% and 64% respectively). 26.5% of the patients had personal history (PH) of thrombosis and 5.5% had PH of Hemorrhagic Diathesis. Table shows the interventions performed and clinical events during the follow-up period.0 post-surgical haemorrhagic events (5%) are described. Three of them (hemoperitoneum after cholecystectomy, hemoperitoneum after laparoscopic tubular gastrectomy, and haematoma of the anterior rectus abdominis muscle with secondary anemization after ventral hernia repair) required hospitalisation for management, all of which were solved with conservative treatment. The other 7 were mild events that were handled outpatiently. In addition, intra-procedure bleeding during bronchoscopy is described in patient with BT, that was controlled on the spot with amchafibrin and adrenaline. No thrombotic events were recorded. Generally, OAT was re-induced the day after surgery in patients undergoing minimal and low HR interventions, being the percentage somewhat lower in patients undergoing high HR interventions, both in high or low TR patients. Summary/Conclusion: Standardization by means of a periprocedural management protocol of the OAT that adjusts BT with LMWH according to the risk factors of each patient, results in a reduction of the incidence of haemorrhagic complications without secondary increase of thromboembolic events. This study demonstrates the importance of centralizing unified periprocedural management using an established protocol.

13.
Annals of Oncology ; 31:S1022-S1022, 2020.
Article in English | PMC | ID: covidwho-1384948

ABSTRACT

Background: The global SARS-CoV-2 outbreak has significantly affected hospital assistance to cancer patients. Diagnostic and treatment paradigms have been challenged with an urgent need for patient protection. In the abscence of data to balance clinical decissions we aimed to analyze HUIS experience during the peak of the outbreak. Method(s): Cancer pts atended at HUIS since February 24th to April 24th were collected. Clinical management was adapted according to evolving international consensus. All PCR+ COVID-19 pts have been included in a database. Oncological and COVID-19 diseases characteristics as well as cancer management have been collected. The main objective of this analysis was to know the risk of SARS-CoV-2 infection, hospitalization rate and mortality of cancer patientes in our center during the outbreak and to identify potential predictive factors. Result(s): Overall, 853 cancer pts had been attended at our department during this period of time. Twenty-six pts (3.05%) were hospitalized with confirmed COVID-19 diagnosis. Underlying solid tumors were the following: breast (256, 30.01%), GI (312, 36.8%), lung (100, 11.72%) and others (185, 21.47%). 322 pts (37.75%) had metastatic cancer and 531 (62.25%) had early stage diseases. 395 pts (46.31%) were treated with antineoplastic agents: 62,63% received treatment as adjuvant therapy, 18. 92% as first line (or maintenance) treatment in advanced diseases and 12.81% second or following lines of treatment in advaced diseases. 10 pts (32.26%) with COVID-19 died. Futher analysis regarding clinical, laboratory and hospital risk factors - such as diagnostic procedures, type and length of treatments, number of hospital visits, etc will be reported in the final presentation. Conclusion(s): COVID-19 hospitalization rate was 3.05%, and mortality rate was 32.26%. Adequate testing and protective measures are mandatory to warrant an optimal managment of cancer pts during the global SARS-CoV-2 outbreak. Legal entity responsible for the study: The authors. Funding(s): Has not received any funding. Disclosure: All authors have declared no conflicts of interest. Copyright © 2020

14.
ACM SIGGRAPH 2021 Immersive Pavilion - International Conference on Computer Graphics and Interactive Techniques, SIGGRAPH 2021 ; 2021.
Article in English | Scopus | ID: covidwho-1373981

ABSTRACT

Virtual staging of real estate listings increases the appeal of a property by letting prospective buyers envision a living space remotely. However, existing tools employed to stage homes limit the scale of the visualization to a set of fixed images provided by customers or require 3D artist expertise to reconstruct the space. The adoption of 3D Matterport scans has accelerated due to the Covid-19 pandemic as a means to enable virtual tours and adhere to social distancing guidelines. We present Home Studio, a virtual staging tool that empowers non-experts, letting them furnish any Matterport scene and create photo-realistic renders in a matter of minutes. Our tool lets customers dive into their designs using a virtual reality headset to assess the final product in an immersive experience. © 2021 Owner/Author.

15.
European Psychiatry ; 64(S1):S674-S675, 2021.
Article in English | ProQuest Central | ID: covidwho-1357388

ABSTRACT

IntroductionCOVID-19 pandemic and lockdown have provoked a considerable psychological impact in Spain. Some studies have reported greater psychological impact in the younger population. To date, no previous study has focused on depressive disorder (DD) patients based on their age.ObjectivesTo describe the psychological impact on DD according to age.MethodsCross-sectional study of an online survey available from 19 to 26 March 2020. Out of a total of 21207 respondents, 608 (2.9%) reported suffering from DD (mean age ±SD = 41.2 years±14.07 [18-82], 80.6% women). The subsample (608) was divided according to age, “youngsters” <45 (57.4%)/ “elders” ≥45. DASS-21 and IES scales were employed. Statistical analyses: Chi-square, t-Student test.ResultsBoth groups did not differ (p>0.05) in sex, having COVID-19 symptoms, having family/friends infected, or income changes. While youngsters were single more frequently (68.8% vs 14.3%, χ² = 179.7, p<0.001), elders had somatic illness more frequently (64.8% vs 39.7% χ² =30.401, p<0.001). Youngsters obtained higher scores in depression (4.69 vs 4.1, T=5.413, p<0.001), anxiety (2.86 vs 1.97, T=5.249, p<0.001) and stress (4.48 vs 3.17, T=6.355, p<0.001) DASS-21 subscales, as in intrusive (3.42 vs 3.05, T=1.984, p=0.048) and avoidant (4.64 vs 4.11, T=3.056, p=0.002) IES scores.ConclusionsDespite the group of elders with depression being more vulnerable to severe COVID-19 disease and presenting more frequently somatic comorbidities, younger depressive patients suffered more from depressive, anxiety, stress and avoidant symptoms and intrusive thoughts, in line with previous reports in the general population.DisclosureNo significant relationships.

16.
European Neuropsychopharmacology ; 40:S475-S476, 2020.
Article in English | EMBASE | ID: covidwho-987706

ABSTRACT

Introduction: After the outbreak of a new coronavirus subtype SARS-CoV-2 in China in late 2019, a global pandemic developed, generating a health, economic, and social emergency [1]. In Spain, the COVID-19 pandemic crisis forced the government to declare a state of emergency on 14 March 2020 and to implement unprecedented lockdown restriction. In this context, patients with severe mental disorders (SMD) may be particularly exposed to stress and social distancing measures [2, 3] and thus disproportionately vulnerable to public health interventions to fight the COVID-19 [4]. However, the early psychological impact of the pandemic and the lockdown in this population is still mostly unknown. Aims of the study: Here, we aim to compare the early psychological impact (depression, anxiety, and stress responses, intrusive and avoidant thoughts, and coping strategies) in a sample of people with SMD compared with two control groups: other mental disorders (OMD) and healthy controls (HC). Methods: An anonymous online questionnaire using a snowball sampling method was conducted from March 19-26, 2020 and included sociodemographic and clinical data along with the Spanish versions of the Depression, Anxiety, and Stress Scale (DASS-21) and the Impact of Event Scale (IES). A total of 21,279 people living in Spain answered the questionnaire, and 125 people with SMD were included in the analysis. Subjects in each of the two control groups (OMD, n = 250;HC, n = 250) were matched (ratio 1:2) for sex and age (± 1 year) with the SMD group. We performed descriptive and bivariate analyses and multinomial and linear regression models. Results: People with SMD [mean age = 43.25 years (SD = 14.41);61.6% females] had statistically significantly higher scores on anxiety, stress, and depression subscales of the DASS-21 compared with the HC group, but lower scores than OMD in all domains (p < 0.05). Most people with SMD (87.2%) were able to enjoy free time, although control groups had higher percentages. After controlling for confounding factors, anxiety was the only significant psychological domain with lower scores in HC than people with SMD (OR = 0.721;95% CI: 0.579 - 0.898). In the SMD group, the multiple linear regression model (R2 = 0.580, F = 41.027, p < 0.001) found that higher anxiety was associated with being single (ẞ = 0.144, t = 2.291, p = 0.024), having COVID-19 symptoms (ẞ = 0.146, t = 2.395, p = 0.018), and a higher score on the stress subscale (ẞ = 0.538, t = 7.635, p < 0.001);whereas being able to enjoy free time was a protective factor (ẞ = -0.244, t = -3.692, p < 0.001). Conclusions: Our results showed that patients with SMD reacted to the pandemic and the lockdown restrictions with higher anxiety levels than the general public, suggesting that this domain could be a criterion for early intervention strategies and closer follow-up. No conflict of interest

17.
European Neuropsychopharmacology ; 40:S393-S394, 2020.
Article in English | EMBASE | ID: covidwho-987698

ABSTRACT

Background: COVID-19 is the pandemic most affected since the 1918 influenza. In order to control its effects, the governments of different countries, including Spain, adopted exceptional measures such as lockdown and the suspension of non-essential economic activity. Studies carried out in China, where the population was also confined, have found an increase in the prevalence of post-traumatic stress symptom among the most affected regions compared to other less affected [1] Aim: To describe the presence of post-traumatic symptom among a large sample from the general population in the different regions of Spain after two weeks from the declaration of the state of alarm in Spain. Methods. The data was obtained through an online questionnaire two weeks after the declaration of the state of alarm in Spain (performed between 19 and 26 March, 2020) addressed to general population over eighteen years old [2]. It was spread using an online “snowball” method. Assessment sociodemographic, clinical variables and psychometric scales. Post-traumatic stress symptoms were measured by the Stressful Impact Scale (EIE), which consists of 15 items, divided into two subscales related to symtoms of intrusion and avoidance. The SPSS v24.0 program was used in the statistical analysis. Results: The sample consists of 21,153 individuals [30.3% men] with an average age of 39.75 ± 14.04 (18 to 100 years). A) Intrusive response: regions with the highest prevalence of intrusive response are Castilla La Mancha (31.2%), Andalusia (30.7%) and Extremadura (26.2%);regions with the lowest prevalence of intrusive response are Aragon (18.9%), Navarra (16.0%) and La Rioja (21.4%). B)Avoidance response: regions with the highest prevalence of avoidance response are Andalusia (55.7%), Extremadura (53.7%) and Castilla La Mancha (51.3%);regions with the lowest prevalence of avoidance response are Galicia (39%), Aragon (37.6%) and Navarra (32.7%). In Madrid, the prevalence of avoidant and intrusive symptoms was 43.1% and 26.0%, respectively. Conclussions: Avoidance symptoms were more frequent than intrusion symptoms in all regions. Andalusia, Extremadura and Castilla La Mancha are the regions with the highest prevalence of post-traumatic stress symptoms, both intrusive and avoidant. In addition, Aragon and Navarra presented low post-traumatic symptoms prevalence. The situation in the Community of Madrid is particularly garish. Despite being the region most affected by the COVID-19 pandemic in Spain, the prevalence of post-traumatic stress symptoms, both intrusive and avoidant, is close to average. The representativeness of the regions in the sample is a limitation of our study. However, the Madrid region is well represented in terms of the percentage share of the total sample. The results obtained do not seem consistent with the epidemiological situation of these regions at that time. It neither are according to the findings of other studies, so it would be necessary to investigate the existence of other factors that contribute to explaining these results. No conflict of interest

18.
European Neuropsychopharmacology ; 40:S374-S375, 2020.
Article in English | EMBASE | ID: covidwho-987695

ABSTRACT

Introduction: We have experienced the effects of an unprecedented pandemic due to the new coronavirus SARS-CoV-2. This is the causative agent of COVID-19. There are precedents for the imposition of lockdown in previous outbreaks that caused a great psychological impact. Specifically, an increase in the mean post-traumatic stress scores, high depressive symptoms and an increase in completed suicides was reported [1,2]. The severity of the impact on mental health is greater in vulnerable people such as those with a psychiatric history [3,4]. Aims: This study aims 1) to assess the psychological impact on a large sample of participants with an anxiety disorder during the onset of the pandemic and lockdown in Spain;2) to Explore differences in the magnitude of the psychological impact of the people with an anxiety disorder according to the sex. Methods: Secondary analyses of a descriptive and comparative cross-sectional study of the data provided by the participants in an anonymous online survey conducted between March 19 and 26. The ad hoc questionnaire included sociodemographic, clinical data and variables related to COVID-19 as well as questions on coping strategies, and the Spanish versions of the Depression, Anxiety and Stress Scale (DASS-21) and the Impact of Event Scale (IES). From the entire sample of 21207 participants, we analyzed 1617 (7.6%) people with an anxiety disorder at that time [mean age = 35.6 (SD = 12.47);women = 1347 (83.3%)]. For the statistical analysis, the sample was divided into two groups according to sex. We used a chi-square test and Student's t test to detect differences among groups. Next, we analyzed the associations between sex and scores on psychometric scales using logistic regression to control for potential confounding factors. Results: Of the individuals with an anxiety disorder, 55.7% were single, 10.2% lived alone and only 2.4% live with family members infected by SARS-CoV-2. 72.8% do not have children in charge, and 89.1% do not have elderly people dependent on them. Comparing the psychological impact between groups, we observed that it is greater in women. We found statistically significant differences in every DASS-21 subscale: depression (4.35 ± 1.19 vs 4.10 ± 1.28;T= -3.076, p<0.002), anxiety (3.20 ± 2.14 vs 2.41 ± 2.03;T= -5.625, p< 0.001) and stress (4.60 ± 2.15 vs 3.86 ± 2.49;T= -4.540, p< 0.001);and in intrusive (3.63 ± 2.07 vs 2.83 ± 2.09;T= -5.751, p< 0.001) and avoidance subscales of IES (4.72 ± 1.89 vs 3.80 ± 2.06;T= -6.850, p< 0.001). Multivariate analysis revealed a statistically significant association of intrusive thoughts (OR 1.12;IC 95%:1.05-1.21, p=0.001), avoidant thoughts (OR 1.19;IC 95%:1.01-1.29, p<0.001) and age (OR 0.99;IC 95%:0.98-0.99, p=0.004) with being female. Conclusions: Our data indicated that the COVID-19 outbreak and lockdown harmed the mental health of people with mental disorders such as anxiety disorders. After considering confounding variables, we observed that women with an anxiety disorder suffer greater negative repercussions such as intrusive and avoidant thoughts compared to men. No conflict of interest

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